| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 8 |
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| Ligand | BDBM19427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_638011 (CHEMBL1166732) |
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| IC50 | >20000±n/a nM |
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| Citation |  Bertrand, P Inside HDAC with HDAC inhibitors. Eur J Med Chem45:2095-116 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 8 |
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| Name: | Histone deacetylase 8 |
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| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41749.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9BY41 |
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| Residue: | 377 |
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| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
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| BDBM19427 |
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| n/a |
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| Name | BDBM19427 |
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| Synonyms: | N-[2-amino-5-(thiophen-2-yl)phenyl]-4-methoxybenzamide | benzamide-type inhibitor, 23 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N2O2S |
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| Mol. Mass. | 324.397 |
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| SMILES | COc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 |
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| Structure | 
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