Reaction Details | |||
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Target | C3a anaphylatoxin chemotactic receptor | ||
Ligand | BDBM50322645 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_642034 (CHEMBL1176066) | ||
EC50 | 470±n/a nM | ||
Citation | Scully, CC; Blakeney, JS; Singh, R; Hoang, HN; Abbenante, G; Reid, RC; Fairlie, DP Selective hexapeptide agonists and antagonists for human complement C3a receptor. J Med Chem53:4938-48 (2010) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
C3a anaphylatoxin chemotactic receptor | |||
Name: | C3a anaphylatoxin chemotactic receptor | ||
Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 53864.66 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_642034 | ||
Residue: | 482 | ||
Sequence: |
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BDBM50322645 | |||
n/a | |||
Name | BDBM50322645 | ||
Synonyms: | (2S,5S,8S,14S,17S)-14-((1H-indol-3-yl)methyl)-17-amino-2-(3-guanidinopropyl)-8-isobutyl-5-methyl-4,7,10,13,16-pentaoxo-18-phenyl-3,6,9,12,15-pentaazaoctadecan-1-oic acid | CHEMBL1170438 | ||
Type | Small organic molecule | ||
Emp. Form. | C37H52N10O7 | ||
Mol. Mass. | 748.8716 | ||
SMILES | CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O |r,wU:38.41,26.28,wD:4.4,43.45,12.24,(13.81,-10.29,;13.81,-8.75,;15.15,-7.98,;12.48,-7.98,;12.48,-6.44,;11.15,-5.67,;9.81,-6.45,;9.81,-7.99,;8.48,-5.68,;7.15,-6.45,;5.81,-5.68,;5.81,-4.14,;4.48,-6.45,;4.48,-7.99,;5.77,-8.83,;7.21,-8.28,;8.17,-9.47,;7.34,-10.77,;7.74,-12.26,;6.65,-13.35,;5.16,-12.95,;4.76,-11.46,;5.85,-10.37,;3.15,-5.68,;1.81,-6.45,;1.81,-7.99,;.48,-5.68,;-.85,-6.44,;.48,-4.14,;1.81,-3.37,;3.15,-4.14,;4.48,-3.37,;4.48,-1.83,;3.15,-1.06,;1.81,-1.83,;13.81,-5.67,;13.81,-4.13,;15.15,-6.44,;16.48,-5.68,;16.48,-4.14,;17.82,-6.45,;17.82,-7.99,;19.15,-5.67,;20.48,-6.44,;20.48,-7.98,;21.82,-8.75,;21.82,-10.29,;23.15,-11.06,;23.15,-12.6,;24.48,-13.38,;21.82,-13.38,;21.82,-5.67,;23.15,-6.44,;21.82,-4.13,)| | ||
Structure |