| Reaction Details |
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 | Report a problem with these data |
| Target | C3a anaphylatoxin chemotactic receptor |
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| Ligand | BDBM50322648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_642034 (CHEMBL1176066) |
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| EC50 | 370±n/a nM |
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| Citation |  Scully, CC; Blakeney, JS; Singh, R; Hoang, HN; Abbenante, G; Reid, RC; Fairlie, DP Selective hexapeptide agonists and antagonists for human complement C3a receptor. J Med Chem53:4938-48 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C3a anaphylatoxin chemotactic receptor |
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| Name: | C3a anaphylatoxin chemotactic receptor |
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| Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53864.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_642034 |
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| Residue: | 482 |
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| Sequence: | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV
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| BDBM50322648 |
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| n/a |
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| Name | BDBM50322648 |
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| Synonyms: | (2S,5S,8S,11S,14S,17S)-14-((1H-indol-3-yl)methyl)-17-amino-2-(3-guanidinopropyl)-11-((R)-1-hydroxyethyl)-8-isobutyl-5-methyl-4,7,10,13,16-pentaoxo-18-phenyl-3,6,9,12,15-pentaazaoctadecan-1-oic acid | CHEMBL1170637 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H56N10O8 |
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| Mol. Mass. | 792.9241 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |r| |
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| Structure | 
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