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TargetBradykinin B1 receptor
LigandBDBM50322868
Substrate/Competitorn/a
Meas. Tech.ChEMBL_644658
Ki 3.4±n/a nM
Citation Liu QQian WLi ABiswas KChen JJFotsch CHan NYuan CArik LBiddlecome GJohnson EKumar GLester-Zeiner DNg GYHungate RWAskew BC Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists. Bioorg Med Chem Lett 20:4593-7 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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  Blast E-value cutoff:
BDBM50322868
n/a
NameBDBM50322868
Synonyms:(R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide | CHEMBL1210754
TypeSmall organic molecule
Emp. Form.C33H36F3N3O3S
Mol. Mass.611.717
SMILESFC(F)(F)c1cccc(c1)S(=O)(=O)N[C@H](CC(=O)N[C@@H]1CCCc2cc(ccc12)C(=C)CNC1CCC1)c1ccccc1 |r|
Structure
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