| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
|---|
| Ligand | BDBM50323040 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_643633 (CHEMBL1212497) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Gattinoni, S; Simone, CD; Dallavalle, S; Fezza, F; Nannei, R; Battista, N; Minetti, P; Quattrociocchi, G; Caprioli, A; Borsini, F; Cabri, W; Penco, S; Merlini, L; Maccarrone, M A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett20:4406-11 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1B |
|---|
| Name: | 5-hydroxytryptamine receptor 1B |
|---|
| Synonyms: | 5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 43173.33 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P28564 |
|---|
| Residue: | 386 |
|---|
| Sequence: | MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPP
FFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMSNEDFKQAFHKLIRFKCTG
|
|
|
|---|
| BDBM50323040 |
|---|
| n/a |
|---|
| Name | BDBM50323040 |
|---|
| Synonyms: | 1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime | CHEMBL1210154 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H16N2O2S |
|---|
| Mol. Mass. | 336.408 |
|---|
| SMILES | CC(=NOC(=O)Nc1ccccc1)c1cccc(c1)-c1cccs1 |w:2.2| |
|---|
| Structure | 
|
|---|
Search and Browse
