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TargetHydroxycarboxylic acid receptor 2
LigandBDBM50323398
Substrate/Competitorn/a
Meas. Tech.ChEMBL_644014
IC50 450±n/a nM
Citation Imbriglio JEChang SLiang RRaghavan SSchmidt DSmenton ATria SSchrader TOJung JKEsser CHolt TGWolff MSTaggart AKCheng KCarballo-Jane EWaters MGTata JRColletti SL GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a. Bioorg Med Chem Lett 20:4472-4 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Hydroxycarboxylic acid receptor 2
Name:Hydroxycarboxylic acid receptor 2
Synonyms:HM74 nicotinic acid GPCR
Type:PROTEIN
Mol. Mass.:41418.01
Organism:Mus musculus
Description:ChEMBL_820676
Residue:360
Sequence:
MSKSDHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSR
IFLFNLAVADFLLIICLPFLTDNYVHNWDWRFGGIPCRVMLFMLAMNRQGSIIFLTVVAV
DRYFRVVHPHHFLNKISNRTAAIISCFLWGLTIGLTVHLLYTNMMTKNGEAYLCSSFSIC
YNFRWHDAMFLLEFFLPLAIILFCSGRIIWSLRQRQMDRHAKIKRAINFIMVVAIVFIIC
FLPSVAVRIRIFWLLYKYNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPN
FFSTCINRCLRKKTLGEPDNNRSTSVELTGDPSTTRSIPGALMADPSEPGSPPYLASTSR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50323398
n/a
NameBDBM50323398
Synonyms:5-(1-methyl-1H-pyrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid | CHEMBL1208986
TypeSmall organic molecule
Emp. Form.C11H12N4O2
Mol. Mass.232.2386
SMILESCn1nccc1C1Cc2[nH]nc(C(O)=O)c2C1
Structure
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