Reaction Details | |||
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Target | Carbapenem-hydrolyzing beta-lactamase KPC | ||
Ligand | BDBM50053173 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_645841 (CHEMBL1218087) | ||
IC50 | 370±n/a nM | ||
Citation | Girlich, D; Poirel, L; Nordmann, P Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. Antimicrob Agents Chemother54:328-32 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Carbapenem-hydrolyzing beta-lactamase KPC | |||
Name: | Carbapenem-hydrolyzing beta-lactamase KPC | ||
Synonyms: | BLKPC_KLEPN | Carbepenem-hydrolyzing beta-lactamase KPC | bla | kpc | kpc1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 31116.99 | ||
Organism: | Klebsiella pneumoniae | ||
Description: | ChEMBL_645841 | ||
Residue: | 293 | ||
Sequence: |
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BDBM50053173 | |||
n/a | |||
Name | BDBM50053173 | ||
Synonyms: | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL404 | CL-298741 | TAZOBACTAM | US9120808, Tazobactam sodium salt | US9676777, TAZ | YTR-830H | Zosyn | ||
Type | Small organic molecule | ||
Emp. Form. | C10H12N4O5S | ||
Mol. Mass. | 300.291 | ||
SMILES | C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |r| | ||
Structure |