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TargetCarbepenem-hydrolyzing beta-lactamase KPC
LigandBDBM50021959
Substrate/Competitorn/a
Meas. Tech.ChEMBL_645841
IC50 10500±n/a nM
Citation Girlich DPoirel LNordmann P Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. Antimicrob Agents Chemother 54:328-32 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbepenem-hydrolyzing beta-lactamase KPC
Name:Carbepenem-hydrolyzing beta-lactamase KPC
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:31116.99
Organism:Klebsiella pneumoniae
Description:ChEMBL_645841
Residue:293
Sequence:
MSLYRRLVLLSCLSWPLAGFSATALTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYR
AEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAE
LSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTS
SPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVY
GTANDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVNGQ
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  Blast E-value cutoff:
BDBM50021959
n/a
NameBDBM50021959
Synonyms:CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
TypeSmall organic molecule
Emp. Form.C8H9NO5
Mol. Mass.199.1608
SMILESOC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure
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