| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor |
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| Ligand | BDBM50323914 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_647642 (CHEMBL1219993) |
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| Ki | 13.01±n/a nM |
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| Citation |  Rivera-Guevara, C; Pérez-Alvarez, V; García-Becerra, R; Ordaz-Rosado, D; Morales-Ríos, MS; Hernández-Gallegos, E; Cooney, AJ; Bravo-Gómez, ME; Larrea, F; Camacho, J Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha. Bioorg Med Chem18:5593-601 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen receptor |
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| Name: | Estrogen receptor |
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| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 |
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| Type: | Protein |
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| Mol. Mass.: | 66230.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03372 |
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| Residue: | 595 |
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| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
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| BDBM50323914 |
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| n/a |
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| Name | BDBM50323914 |
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| Synonyms: | CHEMBL1213786 | Tamoxifen butyl bromide |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38NO |
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| Mol. Mass. | 428.6283 |
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| SMILES | CCCC[N+](C)(C)CCOc1ccc(cc1)C(=C(\CC)c1ccccc1)\c1ccccc1 |
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| Structure | 
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