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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 9 | ||
| Ligand | BDBM50324494 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_649274 (CHEMBL1218972) | ||
| Ki | 0.9±n/a nM | ||
| Citation |  Meng, W; Brigance, RP; Chao, HJ; Fura, A; Harrity, T; Marcinkeviciene, J; O'Connor, SP; Tamura, JK; Xie, D; Zhang, Y; Klei, HE; Kish, K; Weigelt, CA; Turdi, H; Wang, A; Zahler, R; Kirby, MS; Hamann, LG Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. J Med Chem53:5620-8 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 9 | |||
| Name: | Dipeptidyl peptidase 9 | ||
| Synonyms: | DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 98260.70 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q86TI2 | ||
| Residue: | 863 | ||
| Sequence: |
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| BDBM50324494 | |||
| n/a | |||
| Name | BDBM50324494 | ||
| Synonyms: | 6-(aminomethyl)-5-(2,4-dichlorophenyl)-N-(1,3-dimethyl-1H-pyrazol-5-yl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamide | CHEMBL1215089 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H19Cl2N7O | ||
| Mol. Mass. | 444.317 | ||
| SMILES | Cc1cc(NC(=O)c2cn3c(c(CN)c(C)nc3n2)-c2ccc(Cl)cc2Cl)n(C)n1 |(-2.95,-5.54,;-1.73,-4.59,;-.25,-5.02,;.61,-3.75,;2.15,-3.7,;2.88,-2.34,;2.07,-1.03,;4.42,-2.29,;5.36,-3.51,;6.81,-2.99,;8.16,-3.72,;9.47,-2.92,;10.83,-3.64,;12.14,-2.83,;9.42,-1.37,;10.73,-.55,;8.06,-.65,;6.76,-1.46,;5.29,-1.03,;8.13,-5.26,;6.78,-5.99,;6.75,-7.53,;8.07,-8.33,;8.04,-9.87,;9.42,-7.58,;9.45,-6.05,;10.79,-5.3,;-.33,-2.53,;.1,-1.06,;-1.78,-3.05,)| | ||
| Structure | 
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