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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50324835
Substrate/Competitorn/a
Meas. Tech.ChEMBL_651475
Ki 0.300000±n/a nM
Citation Beattie DBradley MBrearley ACharlton SJCuenoud BMFairhurst RAGedeck PGosling MJanus DJones DLewis CMcCarthy COakman HStringer RTaylor RJTuffnell A A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators. Bioorg Med Chem Lett 20:5302-7 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50324835
n/a
NameBDBM50324835
Synonyms:(R)-4-hydroxy-7-(1-hydroxy-2-(3-(methyl(phenyl)amino)propylamino)ethyl)benzo[d]thiazol-2(3H)-one | CHEMBL1221804
TypeSmall organic molecule
Emp. Form.C19H23N3O3S
Mol. Mass.373.469
SMILESCN(CCCNC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12)c1ccccc1 |r|
Structure
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