| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50325609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_652269 (CHEMBL1225472) |
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| Ki | 6.7±n/a nM |
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| Citation |  Weiss, S; Keller, M; Bernhardt, G; Buschauer, A; König, B N(G)-Acyl-argininamides as NPY Y(1) receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity. Bioorg Med Chem18:6292-304 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50325609 |
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| n/a |
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| Name | BDBM50325609 |
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| Synonyms: | (R)-2-{4-[4-(Ammoniomethyl)-1H-1,2,3-triazol-1-yl]butanoyl}-1-[4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentyl]guanidinium 2,2,2-trifluoroacetate | CHEMBL1223997 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H41N9O4 |
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| Mol. Mass. | 639.7472 |
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| SMILES | NCc1cn(CCCC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NCc2ccc(O)cc2)nn1 |r,w:13.13| |
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| Structure | 
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