| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteine protease |
|---|
| Ligand | BDBM50325650 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_652322 (CHEMBL1225525) |
|---|
| Ki | 360±n/a nM |
|---|
| Citation |  Waag, T; Gelhaus, C; Rath, J; Stich, A; Leippe, M; Schirmeister, T Allicin and derivates are cysteine protease inhibitors with antiparasitic activity. Bioorg Med Chem Lett20:5541-3 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cysteine protease |
|---|
| Name: | Cysteine protease |
|---|
| Synonyms: | Rhodesain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48425.78 |
|---|
| Organism: | Trypanosoma brucei rhodesiense |
|---|
| Description: | ChEMBL_619861 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MPRTEMVRFVRLPVVLLAMAACLASVALGSLHVEESLEMRFAAFKKKYGKVYKDAKEEAF
RFRAFEENMEQAKIQAAANPYATFGVTPFSDMTREEFRARYRNGASYFAAAQKRLRKTVN
VTTGRAPAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVS
CDTIDFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDH
VDLPQDEDAIAAYLAENGPLAIAVDATSFMDYNGGILTSCTSEQLDHGVLLVGYNDSSNP
PYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVVGGPTPPPPPPPPPSATFTQDF
CEGKGCTKGCSHATFPTGECVQTTGVGSVIATCGASNLTQIIYPLSRSCSGLSVPITVPL
DKCIPILIGSVEYHCSTNPPTKAARLVPHQ
|
|
|
|---|
| BDBM50325650 |
|---|
| n/a |
|---|
| Name | BDBM50325650 |
|---|
| Synonyms: | CHEMBL1224170 | S-isopentyl 3-methylbutane-1-sulfinothioate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H22OS2 |
|---|
| Mol. Mass. | 222.411 |
|---|
| SMILES | CC(C)CCSS(=O)CCC(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
