| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
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| Ligand | BDBM50326014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_654655 (CHEMBL1243699) |
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| IC50 | 940±n/a nM |
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| Citation |  Love, KR; Catic, A; Schlieker, C; Ploegh, HL Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat Chem Biol3:697-705 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
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| Synonyms: | Neuron cytoplasmic protein 9.5 | PGP 9.5 | PGP9.5 | UCH-L1 | UCHL1 | UCHL1_HUMAN | Ubiquitin thioesterase L1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24819.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_974327 |
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| Residue: | 223 |
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| Sequence: | MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE
NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE
TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP
FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
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| BDBM50326014 |
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| n/a |
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| Name | BDBM50326014 |
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| Synonyms: | 3-(acetoxyimino)-1-(3,4-dichlorobenzyl)-5-iodoindolin-2-one | CHEMBL1241765 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11Cl2IN2O3 |
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| Mol. Mass. | 489.091 |
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| SMILES | CC(=O)ON=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(I)cc12 |w:4.3| |
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| Structure | 
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