| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 3 |
|---|
| Ligand | BDBM50326216 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_659436 (CHEMBL1248346) |
|---|
| IC50 | 5.3±n/a nM |
|---|
| Citation |  Sun, H; Lu, J; Liu, L; Yi, H; Qiu, S; Yang, CY; Deschamps, JR; Wang, S Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins. J Med Chem53:6361-7 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Baculoviral IAP repeat-containing protein 3 |
|---|
| Name: | Baculoviral IAP repeat-containing protein 3 |
|---|
| Synonyms: | API2 | BIRC3 | BIRC3_HUMAN | Baculoviral IAP repeat-containing protein 3 | Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3) | Inhibitor of apoptosis protein 3 (cIAP2) | MIHC | RNF49 | XIAP-BIR3 | cIAP1/cIAP2 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68365.75 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13489 |
|---|
| Residue: | 604 |
|---|
| Sequence: | MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGV
NDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNS
THSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQ
DTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR
CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDL
LNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHD
VIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVS
DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVR
TFLS
|
|
|
|---|
| BDBM50326216 |
|---|
| n/a |
|---|
| Name | BDBM50326216 |
|---|
| Synonyms: | (3S,6S,9R,10aR)-6-((S)-2-(Methylamino)propanamido)-5-oxo-9-(2-phenylacetamido)-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)decahydropyrrolo[1,2-a]azocine-3-carboxamide | CHEMBL1241426 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H43N5O4 |
|---|
| Mol. Mass. | 573.7256 |
|---|
| SMILES | CN[C@@H](C)C(=O)N[C@H]1CC[C@H](C[C@H]2CC[C@H](N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12)NC(=O)Cc1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
