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TargetEnoyl-acyl carrier reductase ENR
LigandBDBM50326319
Substrate/Competitorn/a
Meas. Tech.ChEMBL_657369 (CHEMBL1246345)
IC50 2800±n/a nM
Citation Tipparaju, SKMuench, SPMui, EJRuzheinikov, SNLu, JZHutson, SLKirisits, MJPrigge, STRoberts, CWHenriquez, FLKozikowski, APRice, DWMcLeod, RL Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase. J Med Chem53:6287-300 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-acyl carrier reductase ENR
Name:Enoyl-acyl carrier reductase ENR
Synonyms:Enoyl-acyl carrier reductase | Enoyl-acyl carrier reductase (ENR) | Enoyl-acyl carrier reductase, putative
Type:PROTEIN
Mol. Mass.:43663.67
Organism:Toxoplasma gondii
Description:ChEMBL_1290812
Residue:417
Sequence:
MVGFKLLTLGAFVAGELTLVGPAGTMAFTVPNATGAKPLVTSVSVRPSWSSARQNAFSSS
SSRSQSSVRPHSAFVTNRLETAGETGTQHRAADSAAGVGAAQSAFPIDLRGQTAFVAGVA
DSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGSLIEFAGVYP
LDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVHSLANGPEVTKPL
LETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAERVVPGYGGGMSSAKA
ALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFIDYAIDYSYNNAPLR
RDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVDSRSMPPLQRATQEIN
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  Blast E-value cutoff:
BDBM50326319
n/a
NameBDBM50326319
Synonyms:5-chloro-2-(pyridin-3-yloxy)phenol | CHEMBL1240915
TypeSmall organic molecule
Emp. Form.C11H8ClNO2
Mol. Mass.221.64
SMILESOc1cc(Cl)ccc1Oc1cccnc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: