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TargetEnoyl-acyl carrier reductase
LigandBDBM50326325
Substrate/Competitorn/a
Meas. Tech.ChEMBL_657369
IC50>20000±n/a nM
Citation Tipparaju SKMuench SPMui EJRuzheinikov SNLu JZHutson SLKirisits MJPrigge STRoberts CWHenriquez FLKozikowski APRice DWMcLeod RL Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase. J Med Chem 53:6287-300 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-acyl carrier reductase
Name:Enoyl-acyl carrier reductase
Synonyms:Enoyl-acyl carrier reductase (ENR) | Enoyl-acyl carrier reductase, putative
Type:PROTEIN
Mol. Mass.:43663.67
Organism:Toxoplasma gondii
Description:ChEMBL_1290812
Residue:417
Sequence:
MVGFKLLTLGAFVAGELTLVGPAGTMAFTVPNATGAKPLVTSVSVRPSWSSARQNAFSSS
SSRSQSSVRPHSAFVTNRLETAGETGTQHRAADSAAGVGAAQSAFPIDLRGQTAFVAGVA
DSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGSLIEFAGVYP
LDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVHSLANGPEVTKPL
LETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAERVVPGYGGGMSSAKA
ALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFIDYAIDYSYNNAPLR
RDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVDSRSMPPLQRATQEIN
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  Blast E-value cutoff:
BDBM50326325
n/a
NameBDBM50326325
Synonyms:1-(2-chloro-4-nitrobenzyl)-4-(benzyloxy)pyridin-2(1H)-one | 4-(benzyloxy)-1-(2-chloro-4-nitrobenzyl)pyridin-2(1H)-one | CHEMBL260771
TypeSmall organic molecule
Emp. Form.C19H15ClN2O4
Mol. Mass.370.786
SMILES[O-][N+](=O)c1ccc(Cn2ccc(OCc3ccccc3)cc2=O)c(Cl)c1
Structure
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