| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl carrier reductase ENR |
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| Ligand | BDBM50326332 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_657369 (CHEMBL1246345) |
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| IC50 | >20000±n/a nM |
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| Citation |  Tipparaju, SK; Muench, SP; Mui, EJ; Ruzheinikov, SN; Lu, JZ; Hutson, SL; Kirisits, MJ; Prigge, ST; Roberts, CW; Henriquez, FL; Kozikowski, AP; Rice, DW; McLeod, RL Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase. J Med Chem53:6287-300 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl carrier reductase ENR |
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| Name: | Enoyl-acyl carrier reductase ENR |
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| Synonyms: | Enoyl-acyl carrier reductase | Enoyl-acyl carrier reductase (ENR) | Enoyl-acyl carrier reductase, putative |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43663.67 |
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| Organism: | Toxoplasma gondii |
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| Description: | ChEMBL_1290812 |
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| Residue: | 417 |
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| Sequence: | MVGFKLLTLGAFVAGELTLVGPAGTMAFTVPNATGAKPLVTSVSVRPSWSSARQNAFSSS
SSRSQSSVRPHSAFVTNRLETAGETGTQHRAADSAAGVGAAQSAFPIDLRGQTAFVAGVA
DSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGSLIEFAGVYP
LDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVHSLANGPEVTKPL
LETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAAERVVPGYGGGMSSAKA
ALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSFIDYAIDYSYNNAPLR
RDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLHAMGQAVDSRSMPPLQRATQEIN
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| BDBM50326332 |
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| n/a |
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| Name | BDBM50326332 |
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| Synonyms: | 2-Amino-N-(5-chloro-2-phenoxyphenyl)nicotinamide | CHEMBL1243054 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14ClN3O2 |
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| Mol. Mass. | 339.776 |
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| SMILES | Nc1ncccc1C(=O)Nc1cc(Cl)ccc1Oc1ccccc1 |
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| Structure | 
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