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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50326545
Substrate/Competitorn/a
Meas. Tech.ChEMBL_658303
EC50 0.05±n/a nM
Citation Glossop PALane CAPrice DABunnage MELewthwaite RAJames KBrown ADYeadon MPerros-Huguet CTrevethick MAClarke NPWebster RJones RMBurrows JLFeeder NTaylor SCSpence FJ Inhalation by design: novel ultra-long-actingß(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfonamide agonist headgroup. J Med Chem 53:6640-52 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50326545
n/a
NameBDBM50326545
Synonyms:CHEMBL1243407 | MJ-9184-1,(+/-) | Zinterol
TypeSmall organic molecule
Emp. Form.C19H26N2O4S
Mol. Mass.378.486
SMILESCC(C)(Cc1ccccc1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1
Structure
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