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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | MHC class II antigen | ||
| Ligand | BDBM50326699 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_661466 (CHEMBL1252964) | ||
| IC50 | 4±n/a nM | ||
| Citation |  Venkatraman, P; Nguyen, TT; Sainlos, M; Bilsel, O; Chitta, S; Imperiali, B; Stern, LJ Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol3:222-8 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| MHC class II antigen | |||
| Name: | MHC class II antigen | ||
| Synonyms: | DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 29917.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_192854 | ||
| Residue: | 266 | ||
| Sequence: |
| ||
| BDBM50326699 | |||
| n/a | |||
| Name | BDBM50326699 | ||
| Synonyms: | (2S,5S,8S,11S,14S,17S,20S,23S,26S)-2-amino-1-(5-(dimethylamino)-1,3-dioxoisoindolin-2-yl)-5-(3-guanidinopropyl)-8-(hydroxymethyl)-14,17,20,23,28-pentamethyl-11-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24-octaoxo-4,7,10,13,16,19,22,25-octaazanonacosane-26-carboxylic acid | CHEMBL1253322 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C45H72N14O13S | ||
| Mol. Mass. | 1049.204 | ||
| SMILES | [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#7]-1-[#6](=O)-c2ccc(cc2-[#6]-1=O)-[#7](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| | ||
| Structure | 
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