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TargetMHC class II antigen
LigandBDBM50326701
Substrate/Competitorn/a
Meas. Tech.ChEMBL_661466 (CHEMBL1252964)
IC50>1000±n/a nM
Citation Venkatraman, PNguyen, TTSainlos, MBilsel, OChitta, SImperiali, BStern, LJ Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol3:222-8 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
MHC class II antigen
Name:MHC class II antigen
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
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  Blast E-value cutoff:
BDBM50326701
n/a
NameBDBM50326701
Synonyms:(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(5-(dimethylamino)-1,3-dioxoisoindolin-2-yl)propanoic acid | CHEMBL1254609
TypeSmall organic molecule
Emp. Form.C28H25N3O6
Mol. Mass.499.5146
SMILESCN(C)c1ccc2C(=O)N(C[C@H](NC(=O)OCC3c4ccccc4-c4ccccc34)C(O)=O)C(=O)c2c1 |r|
Structure
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