| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50326709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_662794 (CHEMBL1252533) |
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| IC50 | 2.8±n/a nM |
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| Citation |  Huang, H; Player, MR Bradykinin B1 receptor antagonists as potential therapeutic agents for pain. J Med Chem53:5383-99 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1R | B1bkr | BK-1 receptor | BKRB1_RAT | Bdkrb1 | Bkr | Bradykinin B1 receptor | KB1 | Kinin B1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38389.97 |
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| Organism: | RAT |
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| Description: | B1 BRADYKININ BDKRB1 RAT::P97583 |
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| Residue: | 337 |
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| Sequence: | MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSF
FLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLC
RVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSI
PTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLR
GQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEIT
DLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
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| BDBM50326709 |
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| n/a |
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| Name | BDBM50326709 |
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| Synonyms: | (R)-1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(4-(4-(pyridin-4-yl)piperazin-1-yl)phenyl)urea | CHEMBL1253497 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H39N7O2 |
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| Mol. Mass. | 601.7406 |
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| SMILES | CCCN1c2ccccc2C(CCc2ccccc2)=N[C@@H](NC(=O)Nc2ccc(cc2)N2CCN(CC2)c2ccncc2)C1=O |r,c:20| |
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| Structure | 
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