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TargetCytochrome c oxidase subunit 2
LigandBDBM50326829
Substrate/Competitorn/a
Meas. Tech.ChEMBL_662815 (CHEMBL1252215)
IC50 77±n/a nM
Citation Zarghi, AGhodsi, R Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors. Bioorg Med Chem18:5855-60 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cytochrome c oxidase subunit 2
Name:Cytochrome c oxidase subunit 2
Synonyms:COII | COX2 | COX2_SHEEP | COXII | Cytochrome c oxidase polypeptide II | MT-CO2 | MTCO2
Type:PROTEIN
Mol. Mass.:25987.16
Organism:Ovis aries
Description:ChEMBL_662815
Residue:227
Sequence:
MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQE
VETIWTILPAIILIMIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDS
YMIPTSELKPGELRLLEVDNRVVLPMEMTVRMLISSEDVLPSWAVPSLGLKTDAIPGRLN
QTTLMSTRPGLFYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50326829
n/a
NameBDBM50326829
Synonyms:6-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-carboxylic acid | CHEMBL1254785
TypeSmall organic molecule
Emp. Form.C24H17NO5S
Mol. Mass.431.46
SMILESCS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2cc(ccc2n1)C(=O)c1ccccc1
Structure
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