| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50327508 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_664644 (CHEMBL1260358) |
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| Ki | >1000±n/a nM |
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| Citation |  Lee, DY; Yang, L; Xu, W; Deng, G; Guo, L; Liu-Chen, LY Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A. Bioorg Med Chem Lett20:5749-52 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50327508 |
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| n/a |
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| Name | BDBM50327508 |
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| Synonyms: | (2R,3aS,6aS,7R,9R)-9-Bromo-2-furan-3-yl-3a,6a-dimethyl-2,3,3a,4,5,6,6a,7,8,9-decahydro-benzo[de]chromene-4,7-dicarboxylic acid 7-methyl este r | CHEMBL1257730 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25BrO6 |
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| Mol. Mass. | 453.324 |
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| SMILES | COC(=O)[C@@H]1C[C@@H](Br)C2=C3[C@@]1(C)CCC(C(O)=O)[C@]3(C)C[C@@H](O2)c1ccoc1 |r,c:8| |
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| Structure | 
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