| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
|---|
| Ligand | BDBM50327863 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_664966 (CHEMBL1259923) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Xu, R; Hong, J; Morse, CL; Pike, VW Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography. J Med Chem53:7035-47 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M5 |
|---|
| Name: | Muscarinic acetylcholine receptor M5 |
|---|
| Synonyms: | ACM5_HUMAN | CHRM5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60102.35 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1517990 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
|
|
|
|---|
| BDBM50327863 |
|---|
| n/a |
|---|
| Name | BDBM50327863 |
|---|
| Synonyms: | (1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate | CHEMBL1258671 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H27FN2O4 |
|---|
| Mol. Mass. | 366.4271 |
|---|
| SMILES | CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
