| Reaction Details |
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 | Report a problem with these data |
| Target | Protein arginine N-methyltransferase 1 [11-371] |
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| Ligand | BDBM50328753 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675342 (CHEMBL1273379) |
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| IC50 | 325000±n/a nM |
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| Citation |  Feng, Y; Li, M; Wang, B; Zheng, YG Discovery and mechanistic study of a class of protein arginine methylation inhibitors. J Med Chem53:6028-39 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein arginine N-methyltransferase 1 [11-371] |
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| Name: | Protein arginine N-methyltransferase 1 [11-371] |
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| Synonyms: | ANM1_HUMAN | HMT2 | HRMT1L2 | IR1B4 | PRMT1 | Protein arginine N-methyltransferase 1 (PRMT1) | Protein arginine methyltransferase 1 (PRMT1) | Protein-arginine N-methyltransferase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 41506.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99873[11-371] |
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| Residue: | 361 |
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| Sequence: | MENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDE
VRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIV
KANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGL
IFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNAC
LIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYT
HWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRM
R
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| BDBM50328753 |
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| n/a |
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| Name | BDBM50328753 |
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| Synonyms: | 5-amino-4-hydroxy-3-((4-sulfonatophenyl)diazenyl)naphthalene-2,7-disulfonate | CHEMBL1269836 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13N3O10S3 |
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| Mol. Mass. | 503.484 |
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| SMILES | Nc1cc(cc2cc(c(N=Nc3ccc(cc3)S(O)(=O)=O)c(O)c12)S(O)(=O)=O)S(O)(=O)=O |w:9.8| |
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| Structure | 
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