| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM22541 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_673776 (CHEMBL1274953) |
|---|
| IC50 | 1±n/a nM |
|---|
| Citation |  Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Investigation of 4-piperidinols as novel H3 antagonists. Bioorg Med Chem Lett20:6246-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HH3R | HRH3_MOUSE | Hrh3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48560.37 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_988451 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
|
|
|
|---|
| BDBM22541 |
|---|
| n/a |
|---|
| Name | BDBM22541 |
|---|
| Synonyms: | Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide | VUF 9153 | VUF-9153 | VUF9153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H17ClN4S |
|---|
| Mol. Mass. | 308.83 |
|---|
| SMILES | NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| |
|---|
| Structure | 
|
|---|
Search and Browse
