| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50328812 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_673776 (CHEMBL1274953) |
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| IC50 | 690±n/a nM |
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| Citation |  Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Investigation of 4-piperidinols as novel H3 antagonists. Bioorg Med Chem Lett20:6246-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_MOUSE | Hrh3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48560.37 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_988451 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50328812 |
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| n/a |
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| Name | BDBM50328812 |
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| Synonyms: | CHEMBL1270264 | rac-1,2,5-trimethyl-4-(quinolin-5-ylethynyl)piperidin-4-ol |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2O |
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| Mol. Mass. | 294.3908 |
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| SMILES | CC1CC(O)(C#Cc2cccc3ncccc23)C(C)CN1C |
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| Structure | 
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