| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-oxoacyl-acyl-carrier protein reductase |
|---|
| Ligand | BDBM50329257 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_675155 (CHEMBL1273012) |
|---|
| Ki | 14300±n/a nM |
|---|
| Citation |  Tasdemir, D; Sanabria, D; Lauinger, IL; Tarun, A; Herman, R; Perozzo, R; Zloh, M; Kappe, SH; Brun, R; Carballeira, NM 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorg Med Chem18:7475-85 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-oxoacyl-acyl-carrier protein reductase |
|---|
| Name: | 3-oxoacyl-acyl-carrier protein reductase |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33333.53 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | ChEMBL_675156 |
|---|
| Residue: | 301 |
|---|
| Sequence: | MSVLHRFYLFFLFTKFFHCYKISYVLKNAKLAPNHAIKNINSLNLLSENKKENYYYCGEN
KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSK
KEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPIS
KRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPG
FISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGLS
P
|
|
|
|---|
| BDBM50329257 |
|---|
| n/a |
|---|
| Name | BDBM50329257 |
|---|
| Synonyms: | 2-Hexadecynoic acid | CHEMBL1269411 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H30O2 |
|---|
| Mol. Mass. | 266.4189 |
|---|
| SMILES | CCCCCCCCCCCCCCC#CC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
