| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50068366 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675650 (CHEMBL1274011) |
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| Ki | 4.97±n/a nM |
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| Citation |  Lacivita, E; De Giorgio, P; Lee, IT; Rodeheaver, SI; Weiss, BA; Fracasso, C; Caccia, S; Berardi, F; Perrone, R; Zhang, MR; Maeda, J; Higuchi, M; Suhara, T; Schetz, JA; Leopoldo, M Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptors. J Med Chem53:7344-55 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41307.65 |
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| Organism: | RAT |
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| Description: | DOPAMINE D4.4 0 RAT::P30729 |
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| Residue: | 387 |
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| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
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| BDBM50068366 |
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| n/a |
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| Name | BDBM50068366 |
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| Synonyms: | CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-methoxy-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24ClN3O2 |
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| Mol. Mass. | 373.876 |
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| SMILES | COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccc(Cl)cc1 |
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| Structure | 
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