| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM50417227 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675685 (CHEMBL1274046) |
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| Ki | 501.19±n/a nM |
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| Citation |  Li, YH; Tseng, PS; Evans, KA; Jaworski, JP; Morrow, DM; Fries, HE; Wu, CW; Edwards, RM; Jin, J 3-Urea-1-(phenylmethyl)-pyridones as novel, potent, and selective EP3 receptor antagonists. Bioorg Med Chem Lett20:6744-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 43335.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43115 |
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| Residue: | 390 |
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| Sequence: | MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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| BDBM50417227 |
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| n/a |
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| Name | BDBM50417227 |
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| Synonyms: | CHEMBL1271973 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19Cl2N3O2 |
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| Mol. Mass. | 416.3 |
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| SMILES | CCc1cccc(NC(=O)Nc2cc(Cl)cn(Cc3ccccc3Cl)c2=O)c1 |
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| Structure | 
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