| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50329855 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675737 (CHEMBL1272371) |
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| Kd | 1400±n/a nM |
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| Citation |  Potter, A; Oldfield, V; Nunns, C; Fromont, C; Ray, S; Northfield, CJ; Bryant, CJ; Scrace, SF; Robinson, D; Matossova, N; Baker, L; Dokurno, P; Surgenor, AE; Davis, B; Richardson, CM; Murray, JB; Moore, JD Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution. Bioorg Med Chem Lett20:6483-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50329855 |
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| n/a |
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| Name | BDBM50329855 |
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| Synonyms: | 2-(3-chlorophenyl)-4-(dibenzylcarbamoyl)-1H-imidazole-5-carboxylic acid | CHEMBL1272192 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20ClN3O3 |
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| Mol. Mass. | 445.898 |
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| SMILES | OC(=O)c1nc([nH]c1C(=O)N(Cc1ccccc1)Cc1ccccc1)-c1cccc(Cl)c1 |
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| Structure | 
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