| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphotransferase pUL97 |
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| Ligand | BDBM50330328 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_681653 (CHEMBL1282584) |
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| Ki | 3±n/a nM |
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| Citation |  Gentry, BG; Kamil, JP; Coen, DM; Zemlicka, J; Drach, JC Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir. Antimicrob Agents Chemother54:3093-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphotransferase pUL97 |
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| Name: | Phosphotransferase pUL97 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76103.79 |
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| Organism: | Human cytomegalovirus |
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| Description: | ChEMBL_681653 |
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| Residue: | 688 |
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| Sequence: | MSSALRSRARSASLGTTTQGWDPPPLRRPSRARRRQWMREAAQAAAQAAVQAAQAAAAQV
AQAHVDEDEVVDLMADEAGGGVTTLTTLSSVSTTTVLGHATFSACVRSDVMRDGEKEDAA
SDKENLRRPVVPSTSSRGSAASGDGYHGLRCRETSAMWSFEYDRDGDVTSVRRALFTGGS
DPSDSVSGVRGGRKRPLRPPLVSLARTPLCRRRVGGVDAVLEENDVELRAESQDSAVASG
PGRVPQPLSGSSGEESATAVEADSTSHDDVHCTCSNDQIITTSIRGLTCDPRMFLRLTHP
ELCELSISYLLVYVPKEDDFCHKICYAVDMSDESYRLGQGSFGEVWPLDRYRVVKVARKH
SETVLTVWMSGLIRTRAAGEQQQPPSLMGTGVHRGLLTATGCCLLHNVTVHRRFHTDMFH
HDQWKLACIDSYRRAFCTLADAIKFLNHQCRVCHFDITPMNVLIDVNPHNPSEIVRAALC
DYSLSEPYPDYNERCVAVFQETGTARRIPNCSHRLRECYHPAFRPMPLQKLLICDPHARF
PVAGLRRYCMSELSALGNVLGFCLMRLLDRRGLDEVRMGTEALLFKHAGAACRALENGKL
THCSDACLLILAAQMSYGACLLGEHGAALVSHTLRFVEAKMSSCRVRAFRRFYHECSQTM
LHEYVRKNVERLLATSDGLYLYNAFRRT
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| BDBM50330328 |
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| n/a |
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| Name | BDBM50330328 |
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| Synonyms: | (Z)-2-amino-9-((2,2-bis(hydroxymethyl)cyclopropylidene)methyl)-1H-purin-6(9H)-one | (Z)-9-((2,2-bis(hydroxymethyl)cyclopropylidene)methyl)-2-amino-1H-purin-6(9H)-one | 2-Amino-9-[2,2-bis-hydroxymethyl-cycloprop-(Z)-ylidenemethyl]-1,9-dihydro-purin-6-one | CHEMBL265948 | cyclopropavir |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13N5O3 |
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| Mol. Mass. | 263.2526 |
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| SMILES | Nc1nc2n(\C=C3\CC3(CO)CO)cnc2c(=O)[nH]1 |
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| Structure | 
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