| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2B1 |
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| Ligand | BDBM50330387 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_684298 (CHEMBL1286936) |
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| Kd | 24000±n/a nM |
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| Citation |  Rosales-Hernández, MC; Mendieta-Wejebe, JE; Trujillo-Ferrara, JG; Correa-Basurto, J Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays. Eur J Med Chem45:4845-55 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2B1 |
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| Name: | Cytochrome P450 2B1 |
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| Synonyms: | CP2B1_RAT | Cyp2b-1 | Cyp2b1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55940.51 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_774167 |
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| Residue: | 491 |
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| Sequence: | MEPTILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLRE
KYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGER
WKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIIC
SIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQE
ILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGT
ETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFS
DLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGAL
KKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKI
PPTYQICFSAR
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| BDBM50330387 |
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| n/a |
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| Name | BDBM50330387 |
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| Synonyms: | 1H-pyrrolidine-1-(4'-hydroxyphenyl)-2,5-dione | CHEMBL1275863 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H9NO3 |
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| Mol. Mass. | 191.1834 |
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| SMILES | Oc1ccc(O)n1-c1ccc(O)cc1 |
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| Structure | 
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