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TargetUridine phosphorylase (UPase)
LigandBDBM50330391
Substrate/Competitorn/a
Meas. Tech.ChEMBL_684504
Ki 1.1±n/a nM
Citation Cui HRuda GFCarrero-Lérida JRuiz-Pérez LMGilbert IHGonzález-Pacanowska D Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase. Eur J Med Chem 45:5140-9 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uridine phosphorylase (UPase)
Name:Uridine phosphorylase (UPase)
Synonyms:UPase 1 | UrdPase 1
Type:Enzyme
Mol. Mass.:33939.54
Organism:Homo sapiens (Human)
Description:Q16831
Residue:310
Sequence:
MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG
SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH
ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT
DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY
AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS
YFIKKKLSKA
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  Blast E-value cutoff:
BDBM50330391
n/a
NameBDBM50330391
Synonyms:5-(3-(benzyloxy)benzyl)-1-((2-hydroxyethoxy)methyl)pyrimidine-2,4,6(1H,3H,5H)-trione | CHEMBL1277898
TypeSmall organic molecule
Emp. Form.C21H22N2O6
Mol. Mass.398.4092
SMILESOCCOCn1c(O)c(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O
Structure
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