| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Purine nucleoside phosphorylase |
|---|
| Ligand | BDBM50330397 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_684503 (CHEMBL1287512) |
|---|
| Ki | 105000±n/a nM |
|---|
| Citation |  Cui, H; Ruda, GF; Carrero-Lérida, J; Ruiz-Pérez, LM; Gilbert, IH; González-Pacanowska, D Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase. Eur J Med Chem45:5140-9 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Purine nucleoside phosphorylase |
|---|
| Name: | Purine nucleoside phosphorylase |
|---|
| Synonyms: | Purine Nucleoside Phosphorylase (PNP) | pfPNP |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26857.85 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | n/a |
|---|
| Residue: | 245 |
|---|
| Sequence: | MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFL
CVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHL
LIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAV
VEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKL
ATKYA
|
|
|
|---|
| BDBM50330397 |
|---|
| n/a |
|---|
| Name | BDBM50330397 |
|---|
| Synonyms: | 1-((4-Pyrrolidine-1-yl)-butyl)uracil | CHEMBL1275702 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H19N3O2 |
|---|
| Mol. Mass. | 237.2982 |
|---|
| SMILES | O=c1ccn(CCCCN2CCCC2)c(=O)[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
