| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PAK 2 |
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| Ligand | BDBM50331277 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_686617 (CHEMBL1292412) |
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| IC50 | >30000±n/a nM |
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| Citation |  Herdemann, M; Heit, I; Bosch, FU; Quintini, G; Scheipers, C; Weber, A Identification of potent ITK inhibitors through focused compound library design including structural information. Bioorg Med Chem Lett20:6998-7003 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase PAK 2 |
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| Name: | Serine/threonine-protein kinase PAK 2 |
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| Synonyms: | PAK2 | PAK2_HUMAN | Serine/threonine-protein kinase PAK 1/PAK 2/PAK 3 | Serine/threonine-protein kinase PAK 2 | Serine/threonine-protein kinase PAK 2 (PAK2) | p21-Activated kinase 2 (PAK2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 58037.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13177 |
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| Residue: | 524 |
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| Sequence: | MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNAKGTEAPAVVTEEEDDDEETAP
PVIAPRPDHTKSIYTRSVIDPVPAPVGDSHVDGAAKSLDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
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| BDBM50331277 |
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| n/a |
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| Name | BDBM50331277 |
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| Synonyms: | 3-(6-methoxy-1H-indol-2-yl)-1H-pyrazolo[4,3-b]pyridine | CHEMBL1288582 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N4O |
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| Mol. Mass. | 264.282 |
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| SMILES | COc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 |
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| Structure | 
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