Reaction Details |
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Target | Ribonuclease pancreatic |
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Ligand | BDBM50331791 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_686759 (CHEMBL1290998) |
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Ki | 67000±n/a nM |
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Citation | Debnath, J; Dasgupta, S; Pathak, T Comparative inhibitory activity of 3'- and 5'-functionalized nucleosides on ribonuclease A. Bioorg Med Chem18:8257-63 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Ribonuclease pancreatic |
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Name: | Ribonuclease pancreatic |
Synonyms: | CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1 |
Type: | Enzyme |
Mol. Mass.: | 16468.79 |
Organism: | Bison bison (American bison) |
Description: | carboxamidomethylated RNase A |
Residue: | 150 |
Sequence: | MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRN
LTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPN
CAYKTTQANKHIIVACEGNPYVPVHFDASV
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BDBM50331791 |
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n/a |
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Name | BDBM50331791 |
Synonyms: | (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-carboxylic acid | 5'-Carboxy adenosine | CHEMBL595547 |
Type | Small organic molecule |
Emp. Form. | C10H11N5O5 |
Mol. Mass. | 281.2248 |
SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)C(O)=O |r| |
Structure |
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