| Reaction Details |
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 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Ligand | BDBM23449 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_687953 (CHEMBL1291625) |
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| IC50 | 3300±n/a nM |
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| Citation |  Nolan, KA; Caraher, MC; Humphries, MP; Bettley, HA; Bryce, RA; Stratford, IJ In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett20:7331-6 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Type: | Protein |
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| Mol. Mass.: | 25917.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16083 |
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| Residue: | 231 |
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| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
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| BDBM23449 |
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| n/a |
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| Name | BDBM23449 |
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| Synonyms: | 1,3-Dihydroxynaphthalene | Naphthalene-1,3-diol | Naphthoresorcinol |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8O2 |
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| Mol. Mass. | 160.1693 |
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| SMILES | Oc1cc(O)c2ccccc2c1 |
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| Structure | 
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