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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 1 | ||
| Ligand | BDBM50332892 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_694005 (CHEMBL1636581) | ||
| Ki | 193.5±n/a nM | ||
| Citation |  Silvestri, R; Ligresti, A; La Regina, G; Piscitelli, F; Gatti, V; Lavecchia, A; Brizzi, A; Pasquini, S; Allarà, M; Fantini, N; Carai, MA; Bigogno, C; Rozio, MG; Sinisi, R; Novellino, E; Colombo, G; Di Marzo, V; Dondio, G; Corelli, F Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands. Eur J Med Chem45:5878-86 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 1 | |||
| Name: | Cannabinoid receptor 1 | ||
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 52868.96 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21554 | ||
| Residue: | 472 | ||
| Sequence: |
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| BDBM50332892 | |||
| n/a | |||
| Name | BDBM50332892 | ||
| Synonyms: | 1-(2,4-Dichlorophenyl)-5-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methyl-N-tert-pentyl-1H-pyrazole-3-carboxamide | CHEMBL1631298 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H26Cl2N4O | ||
| Mol. Mass. | 433.374 | ||
| SMILES | CCC(C)(C)NC(=O)c1nn(c(c1C)-n1c(C)ccc1C)-c1ccc(Cl)cc1Cl |(13.97,-1.89,;13.2,-3.22,;11.66,-3.23,;10.32,-3.98,;11.65,-4.76,;10.89,-1.9,;9.34,-1.9,;8.58,-.58,;8.56,-3.25,;8.98,-4.72,;7.71,-5.58,;6.51,-4.61,;7.05,-3.18,;6.22,-1.87,;4.97,-4.7,;4.05,-3.45,;4.51,-1.98,;2.61,-3.93,;2.6,-5.46,;4.08,-5.93,;4.55,-7.4,;7.7,-7.12,;6.38,-7.89,;6.37,-9.44,;7.71,-10.21,;7.71,-11.75,;9.04,-9.44,;9.04,-7.89,;10.39,-7.1,)| | ||
| Structure | 
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