| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50332949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_694545 (CHEMBL1635954) |
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| Ki | 823±n/a nM |
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| Citation |  Attolino, E; Calderone, V; Dragoni, E; Fragai, M; Richichi, B; Luchinat, C; Nativi, C Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs). Eur J Med Chem45:5919-25 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50332949 |
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| n/a |
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| Name | BDBM50332949 |
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| Synonyms: | (R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)propanamide | CHEMBL1632639 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14N2O6S |
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| Mol. Mass. | 290.293 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N[C@H](CO)C(=O)NO |r| |
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| Structure | 
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