| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Inositol phosphorylceramide synthase |
|---|
| Ligand | BDBM50333120 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_690931 (CHEMBL1634539) |
|---|
| Ki | 16±n/a nM |
|---|
| Citation |  Aeed, PA; Young, CL; Nagiec, MM; Elhammer, AP Inhibition of inositol phosphorylceramide synthase by the cyclic peptide aureobasidin A. Antimicrob Agents Chemother53:496-504 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Inositol phosphorylceramide synthase |
|---|
| Name: | Inositol phosphorylceramide synthase |
|---|
| Synonyms: | AUR1 | AUR1_CANAL | Aureobasidin A resistance protein homolog | IPC synthase | Phosphatidylinositol:ceramide phosphoinositol transferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53452.25 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_690931 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MASSILRSKIIQKPYQLFHYYFLSEKAPGSTVSDLNFDTNIQTSLRKLKHHHWTVGEIFH
YGFLVSILFFVFVVFPASFFIKLPIILAFATCFLIPLTSQFFLPALPVFTWLALYFTCAK
IPQEWKPAITVKVLPAMETILYGDNLSNVLATITTGVLDILAWLPYGIIHFSFPFVLAAI
IFLFGPPTALRSFGFAFGYMNLLGVLIQMAFPAAPPWYKNLHGLEPANYSMHGSPGGLGR
IDKLLGVDMYTTGFSNSSIIFGAFPSLHSGCCIMEVLFLCWLFPRFKFVWVTYASWLWWS
TMYLTHHYFVDLIGGAMLSLTVFEFTKYKYLPKNKEGLFCRWSYTEIEKIDIQEIDPLSY
NYIPINSNDNESRLYTRVYQESQVSPPSRAETPEAFEMSNFSRSRQSSKTQVPLSNLTNN
DQVPGINEEDEEEEGDEISSSTPSVFEDEPQGSTYAASSATSVDDLDSKRN
|
|
|
|---|
| BDBM50333120 |
|---|
| n/a |
|---|
| Name | BDBM50333120 |
|---|
| Synonyms: | CHEMBL1631581 | Rustmicin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H34O5 |
|---|
| Mol. Mass. | 378.5024 |
|---|
| SMILES | CC[C@@H]1CC(=O)[C@H](C)C(=O)[C@@](O)(CO)C\C(OC)=C\[C@@H](C)CC(=C)\C=C1/C |r,t:17,24| |
|---|
| Structure | 
|
|---|
Search and Browse
