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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Deoxyribonuclease gamma | ||
| Ligand | BDBM50206432 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_698124 (CHEMBL1646044) | ||
| IC50 | 30000±n/a nM | ||
| Citation |  Yamada, Y; Fujii, T; Ishijima, R; Tachibana, H; Yokoue, N; Takasawa, R; Tanuma, S DR396, an apoptotic DNase¿ inhibitor, attenuates high mobility group box 1 release from apoptotic cells. Bioorg Med Chem19:168-71 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Deoxyribonuclease gamma | |||
| Name: | Deoxyribonuclease gamma | ||
| Synonyms: | DHP2 | DNAS1L3 | DNASE1L3 | DNSL3_HUMAN | DNase I homolog protein DHP2 | DNase I-like 3 | DNase gamma | Deoxyribonuclease I-like 3 | LS-DNase | LSD | Liver and spleen DNase | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 35519.06 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1457551 | ||
| Residue: | 305 | ||
| Sequence: |
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| BDBM50206432 | |||
| n/a | |||
| Name | BDBM50206432 | ||
| Synonyms: | 4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid | CHEMBL222509 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H12Cl2N4O5 | ||
| Mol. Mass. | 495.271 | ||
| SMILES | OC(=O)c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1-c1c2ccc(O)cc2oc2cc(=O)ccc12 |(23.23,-31.33,;23.79,-29.89,;22.82,-28.7,;25.31,-29.65,;25.3,-28.12,;26.63,-27.33,;27.97,-28.1,;29.3,-27.32,;29.29,-25.78,;27.95,-25.03,;27.94,-23.49,;26.6,-22.73,;29.28,-22.71,;30.61,-23.47,;31.94,-22.69,;30.62,-25.01,;27.98,-29.63,;26.64,-30.4,;26.65,-31.94,;27.99,-32.7,;29.32,-31.92,;30.66,-32.68,;30.67,-34.23,;32.01,-34.99,;29.34,-35.01,;28,-34.25,;26.66,-35.02,;25.33,-34.26,;23.99,-35.04,;22.66,-34.27,;21.33,-35.03,;22.66,-32.72,;23.99,-31.95,;25.33,-32.71,)| | ||
| Structure | 
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