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Target5-hydroxytryptamine receptor 1A (5-HT1A)
LigandBDBM50333436
Substrate/Competitorn/a
Meas. Tech.ChEMBL_698908
Ki 6±n/a nM
Citation Pettersson MCampbell BMDounay ABGray DLXie LO'Donnell CJStratman NCZoski KDrummond EBora GProbert AWhisman T Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT(1A) partial agonists. Bioorg Med Chem Lett 21:865-8 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1A (5-HT1A)
Name:5-hydroxytryptamine receptor 1A (5-HT1A)
Synonyms:5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:n/a
Mol. Mass.:46122.49
Organism:Homo sapiens (Human)
Description:n/a
Residue:422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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  Blast E-value cutoff:
BDBM50333436
n/a
NameBDBM50333436
Synonyms:3-(2-(2,6-dichlorophenoxy)-6-fluorophenoxy)azetidine | CHEMBL1645603
TypeSmall organic molecule
Emp. Form.C15H12Cl2FNO2
Mol. Mass.328.166
SMILESFc1cccc(Oc2c(Cl)cccc2Cl)c1OC1CNC1
Structure
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