| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
|---|
| Ligand | BDBM10859 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_700657 (CHEMBL1645696) |
|---|
| Ki | 1582±n/a nM |
|---|
| Citation |  Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett21:710-4 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 6 |
|---|
| Name: | Carbonic anhydrase 6 |
|---|
| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35371.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P23280 |
|---|
| Residue: | 308 |
|---|
| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
|
|
|
|---|
| BDBM10859 |
|---|
| n/a |
|---|
| Name | BDBM10859 |
|---|
| Synonyms: | 4-methylbenzene-1-sulfonamide | CHEMBL574 | aromatic/heteroaromatic sulfonamide 4 | hCA inhibitor, 7 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H9NO2S |
|---|
| Mol. Mass. | 171.217 |
|---|
| SMILES | Cc1ccc(cc1)S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
