| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_700658 (CHEMBL1645697) |
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| Ki | 20.4±n/a nM |
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| Citation |  Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett21:710-4 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | Alpha carbonic anhydrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36650.57 |
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| Organism: | Stylophora pistillata |
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| Description: | ChEMBL_700658 |
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| Residue: | 323 |
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| Sequence: | MKLSLFISSLLAMIVACPNLAESAGSWTYRDPEGPDTWKHHYKDCEGHEQSPINIVPKDT
FFEPGLADLVVNYEKSVSAKLFNNGHTVQATFLTGKSNISGGNLTSHFRALQMHFHWGSE
NSRGSEHQVGGRKFPLEIHIVHYNAEKYPSVSEAVDKGDGLAVLGILVELQVQDNPVFDV
MVDNLDKARYKGNEVILPSLQPFSFLPHDIAQYYTYRGSLTTPGCFESVQWFVFNHTFPI
SQAQLDKFRDLFDSEKQDTKKLPLVDNYRPVQPLYGRSVSEASNALLFPVARHQTKLWIA
WDSLMTRQYFMKQQSICALYQPQ
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| BDBM10886 |
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| n/a |
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| Name | BDBM10886 |
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| Synonyms: | 2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide | BZA1 | Benzolamide | Benzolamide (BZA) | CHEMBL73962 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H8N4O4S3 |
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| Mol. Mass. | 320.369 |
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| SMILES | NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccccc2)s1 |
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| Structure | 
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