| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50334040 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_701235 (CHEMBL1648855) |
|---|
| EC50 | 70±n/a nM |
|---|
| Citation |  Yang, SW; Smotryski, J; Matasi, J; Ho, G; Tulshian, D; Greenlee, WJ; Brusa, R; Beltramo, M; Cox, K Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain. Bioorg Med Chem Lett21:182-5 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 39690.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34972 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
|
|
|
|---|
| BDBM50334040 |
|---|
| n/a |
|---|
| Name | BDBM50334040 |
|---|
| Synonyms: | 3-methyl-1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)benzyl)piperidine | CHEMBL1644681 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H24F3N3 |
|---|
| Mol. Mass. | 399.452 |
|---|
| SMILES | CC1CCCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
