| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50334044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_701235 (CHEMBL1648855) |
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| EC50 | 8±n/a nM |
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| Citation |  Yang, SW; Smotryski, J; Matasi, J; Ho, G; Tulshian, D; Greenlee, WJ; Brusa, R; Beltramo, M; Cox, K Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain. Bioorg Med Chem Lett21:182-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50334044 |
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| n/a |
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| Name | BDBM50334044 |
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| Synonyms: | 1-(3-(4-(2,3-dichlorophenyl)-1H-imidazol-2-yl)benzyl)piperidine | CHEMBL1644740 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21Cl2N3 |
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| Mol. Mass. | 386.318 |
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| SMILES | Clc1cccc(-c2c[nH]c(n2)-c2cccc(CN3CCCCC3)c2)c1Cl |
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| Structure | 
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