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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Alpha-2A adrenergic receptor | ||
| Ligand | BDBM50334197 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_698563 (CHEMBL1647738) | ||
| EC50 | 73±n/a nM | ||
| Citation |  Saczewski, F; Kornicka, A; Hudson, AL; Laird, S; Scheinin, M; Laurila, JM; Rybczynska, A; Boblewski, K; Lehmann, A; Gdaniec, M 3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for thea(2)-adrenoceptor compared to the imidazoline I(1) receptor. Bioorg Med Chem19:321-9 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Alpha-2A adrenergic receptor | |||
| Name: | Alpha-2A adrenergic receptor | ||
| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 48979.91 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08913 | ||
| Residue: | 450 | ||
| Sequence: |
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| BDBM50334197 | |||
| n/a | |||
| Name | BDBM50334197 | ||
| Synonyms: | 7-Chloro-3-[(imidazolidin-2-yl)imino]indazole hydrochloride | CHEMBL1641689 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C10H10ClN5 | ||
| Mol. Mass. | 235.673 | ||
| SMILES | Clc1cccc2c(N=C3NCCN3)[nH]nc12 |(13.68,-39.86,;13.64,-41.39,;12.29,-42.12,;12.25,-43.67,;13.56,-44.47,;14.92,-43.74,;16.37,-44.25,;17.18,-45.57,;18.71,-45.54,;19.59,-44.27,;21.07,-44.71,;21.09,-46.25,;19.64,-46.76,;17.3,-43.03,;16.43,-41.77,;14.95,-42.2,)| | ||
| Structure | 
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