| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50334257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_699426 (CHEMBL1647453) |
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| Ki | 23.2±n/a nM |
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| Citation |  Nirogi, RV; Deshpande, AD; Kambhampati, R; Badange, RK; Kota, L; Daulatabad, AV; Shinde, AK; Ahmad, I; Kandikere, V; Jayarajan, P; Dubey, PK Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists. Bioorg Med Chem Lett21:346-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50334257 |
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| n/a |
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| Name | BDBM50334257 |
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| Synonyms: | 5-Bromo-1-(4-isopropylbenzenesulfonyl)-3-(4-methylpiperazin-1-yl)-1H-indole | CHEMBL1642421 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26BrN3O2S |
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| Mol. Mass. | 476.43 |
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| SMILES | CC(C)c1ccc(cc1)S(=O)(=O)n1cc(N2CCN(C)CC2)c2cc(Br)ccc12 |
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| Structure | 
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